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Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo
Background. The myeloid enzyme 12/15-lipoxygenase (LOX), which generates bioactive oxidized lipids, has been implicated in numerous inflammatory diseases, with several studies demonstrating an improvement in pathology in mice lacking the enzyme. However, the ability of 12/15-LOX to directly regulate...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321417/ https://www.ncbi.nlm.nih.gov/pubmed/28239665 http://dx.doi.org/10.12688/wellcomeopenres.10308.1 |