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Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo

Background. The myeloid enzyme 12/15-lipoxygenase (LOX), which generates bioactive oxidized lipids, has been implicated in numerous inflammatory diseases, with several studies demonstrating an improvement in pathology in mice lacking the enzyme. However, the ability of 12/15-LOX to directly regulate...

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Detalles Bibliográficos
Autores principales:	Lauder, Sarah N., Tyrrell, Victoria J, Allen-Redpath, Keith, Aldrovandi, Maceler, Gray, David, Collins, Peter, Jones, Simon A, Taylor, Philip R, O'Donnell, Valerie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	F1000Research 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321417/ https://www.ncbi.nlm.nih.gov/pubmed/28239665 http://dx.doi.org/10.12688/wellcomeopenres.10308.1

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