Cargando…

Epileptogenesis in organotypic hippocampal cultures has limited dependence on culture medium composition

Rodent organotypic hippocampal cultures spontaneously develop epileptiform activity after approximately 2 weeks in vitro and are increasingly used as a model of chronic post-traumatic epilepsy. However, organotypic cultures are maintained in an artificial environment (culture medium), which contains...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Jing, Saponjian, Yero, Mahoney, Mark M., Staley, Kevin J., Berdichevsky, Yevgeny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321418/
https://www.ncbi.nlm.nih.gov/pubmed/28225808
http://dx.doi.org/10.1371/journal.pone.0172677