A distal intergenic region controls pancreatic endocrine differentiation by acting as a transcriptional enhancer and as a polycomb response element

Lineage-selective expression of developmental genes is dependent on the interplay between activating and repressive mechanisms. Gene activation is dependent on cell-specific transcription factors that recognize transcriptional enhancer sequences. Gene repression often depends on the recruitment of P...

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Detalles Bibliográficos
Autores principales: van Arensbergen, Joris, Dussaud, Sebastien, Pardanaud-Glavieux, Corinne, García-Hurtado, Javier, Sauty, Claire, Guerci, Aline, Ferrer, Jorge, Ravassard, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321433/
https://www.ncbi.nlm.nih.gov/pubmed/28225770
http://dx.doi.org/10.1371/journal.pone.0171508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321433/
https://www.ncbi.nlm.nih.gov/pubmed/28225770
http://dx.doi.org/10.1371/journal.pone.0171508

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