Pharmacokinetic modeling of [(11)C]flumazenil kinetics in the rat brain

BACKGROUND: Preferred models for the pharmacokinetic analysis of [(11)C]flumazenil human studies have been previously established. However, direct translation of these models and settings to animal studies might be sub-optimal. Therefore, this study evaluates pharmacokinetic models for the quantific...

Descripción completa

Detalles Bibliográficos
Autores principales: Lopes Alves, Isadora, Vállez García, David, Parente, Andrea, Doorduin, Janine, Dierckx, Rudi, Marques da Silva, Ana Maria, Koole, Michel, Willemsen, Antoon, Boellaard, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321646/
https://www.ncbi.nlm.nih.gov/pubmed/28229437
http://dx.doi.org/10.1186/s13550-017-0265-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321646/
https://www.ncbi.nlm.nih.gov/pubmed/28229437
http://dx.doi.org/10.1186/s13550-017-0265-4

Ejemplares similares