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The Structure of the Synaptic Vesicle-Plasma Membrane Interface Constrains SNARE Models of Rapid, Synchronous Exocytosis at Nerve Terminals
Contemporary models of neurotransmitter release invoke direct or indirect interactions between the Ca(2+) sensor, synaptotagmin and the incompletely zippered soluble, N-ethyl-maleimide-sensitive factor attachment protein receptor (SNARE) complex. However, recent electron microscopic (EM) investigati...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321675/ https://www.ncbi.nlm.nih.gov/pubmed/28280457 http://dx.doi.org/10.3389/fnmol.2017.00048 |