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The Structure of the Synaptic Vesicle-Plasma Membrane Interface Constrains SNARE Models of Rapid, Synchronous Exocytosis at Nerve Terminals

Contemporary models of neurotransmitter release invoke direct or indirect interactions between the Ca(2+) sensor, synaptotagmin and the incompletely zippered soluble, N-ethyl-maleimide-sensitive factor attachment protein receptor (SNARE) complex. However, recent electron microscopic (EM) investigati...

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Detalles Bibliográficos
Autor principal: Gundersen, Cameron B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321675/
https://www.ncbi.nlm.nih.gov/pubmed/28280457
http://dx.doi.org/10.3389/fnmol.2017.00048