Mechanism of partial agonism in AMPA-type glutamate receptors

Neurotransmitters trigger synaptic currents by activating ligand-gated ion channel receptors. Whereas most neurotransmitters are efficacious agonists, molecules that activate receptors more weakly—partial agonists—also exist. Whether these partial agonists have weak activity because they stabilize l...

Descripción completa

Detalles Bibliográficos
Autores principales: Salazar, Hector, Eibl, Clarissa, Chebli, Miriam, Plested, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321683/
https://www.ncbi.nlm.nih.gov/pubmed/28211453
http://dx.doi.org/10.1038/ncomms14327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321683/
https://www.ncbi.nlm.nih.gov/pubmed/28211453
http://dx.doi.org/10.1038/ncomms14327

Ejemplares similares