Cargando…
Mechanism of partial agonism in AMPA-type glutamate receptors
Neurotransmitters trigger synaptic currents by activating ligand-gated ion channel receptors. Whereas most neurotransmitters are efficacious agonists, molecules that activate receptors more weakly—partial agonists—also exist. Whether these partial agonists have weak activity because they stabilize l...
Autores principales: | Salazar, Hector, Eibl, Clarissa, Chebli, Miriam, Plested, Andrew |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321683/ https://www.ncbi.nlm.nih.gov/pubmed/28211453 http://dx.doi.org/10.1038/ncomms14327 |
Ejemplares similares
-
The action of Con-ikot-ikot toxin on single AMPA-type glutamate receptors
por: Baranovic, Jelena, et al.
Publicado: (2022) -
Nonselective cation permeation in an AMPA-type glutamate receptor
por: Biedermann, Johann, et al.
Publicado: (2021) -
Control of AMPA receptor activity by the extracellular loops of auxiliary proteins
por: Riva, Irene, et al.
Publicado: (2017) -
Measurements of the Timescale and Conformational Space of AMPA Receptor Desensitization
por: Salazar, Hector, et al.
Publicado: (2020) -
Superactivation of AMPA receptors by auxiliary proteins
por: Carbone, Anna L., et al.
Publicado: (2016)