Expanding the genetic code of Mus musculus

Here we report the expansion of the genetic code of Mus musculus with various unnatural amino acids including N(ɛ)-acetyl-lysine. Stable integration of transgenes encoding an engineered N(ɛ)-acetyl-lysyl-tRNA synthetase (AcKRS)/tRNA(Pyl) pair into the mouse genome enables site-specific incorporation...

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Detalles Bibliográficos
Autores principales: Han, Songmi, Yang, Aerin, Lee, Soonjang, Lee, Han-Woong, Park, Chan Bae, Park, Hee-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321798/
https://www.ncbi.nlm.nih.gov/pubmed/28220771
http://dx.doi.org/10.1038/ncomms14568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321798/
https://www.ncbi.nlm.nih.gov/pubmed/28220771
http://dx.doi.org/10.1038/ncomms14568

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