Multiscale modeling reveals inhibitory and stimulatory effects of caffeine on acetaminophen‐induced toxicity in humans

Acetaminophen (APAP) is a widely used analgesic drug that is frequently co‐administered with caffeine (CAF) in the treatment of pain. It is well known that APAP may cause severe liver injury after an acute overdose. However, the understanding of whether and to what extent CAF inhibits or stimulates...

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Detalles Bibliográficos
Autores principales: Thiel, C, Cordes, H, Baier, V, Blank, LM, Kuepfer, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321810/
https://www.ncbi.nlm.nih.gov/pubmed/28130915
http://dx.doi.org/10.1002/psp4.12153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321810/
https://www.ncbi.nlm.nih.gov/pubmed/28130915
http://dx.doi.org/10.1002/psp4.12153

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