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Secretory phospholipase A2 in the pathogenesis of acute dengue infection

INTRODUCTION: Platelet activating factor (PAF) is an important mediator of vascular leak in acute dengue. Phospholipase A2s (PLA2) are inflammatory lipid enzymes that generate and regulate PAF and other mediators associated with mast cells. We sought to investigate if mast cell activation and increa...

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Detalles Bibliográficos
Autores principales: Jeewandara, Chandima, Gomes, Laksiri, Udari, Sukhitha, Paranavitane, S.A., Shyamali, N.L.A., Ogg, Graham S., Malavige, Gathsaurie Neelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322161/
https://www.ncbi.nlm.nih.gov/pubmed/28250920
http://dx.doi.org/10.1002/iid3.135