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LKB1 Inhibits HPV-Associated Cancer Progression by Targeting Cellular Metabolism

Liver kinase B1 (LKB1) is mutationally inactivated in Peutz-Jeghers syndrome and in a variety of cancers including human papillomavirus (HPV)-caused cervical cancer. However, the significance of LKB1 mutations in cervical cancer initiation and progress has not been examined. Herein, we demonstrated...

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Detalles Bibliográficos
Autores principales: Zeng, Qinghua, Chen, Jianfeng, Li, Yining, Werle, Kaitlin D., Zhao, Rui-Xun, Quan, Cheng-Shi, Wang, Yi-Shu, Zhai, Ying-Xian, Wang, Jian-Wei, Youssef, Mariam, Cui, Rutao, Liang, Jiyong, Genovese, Nicholas, Chow, Louise T., Li, Yu-Lin, Xu, Zhi-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322260/
https://www.ncbi.nlm.nih.gov/pubmed/27546620
http://dx.doi.org/10.1038/onc.2016.290