Endogenous Leucine-Rich Repeat Kinase 2 Slows Synaptic Vesicle Recycling in Striatal Neurons

Dominant mutations in leucine-rich repeat kinase 2 (LRRK2) produce the most common inherited form of Parkinson’s disease (PD) but the function of LRRK2 remains poorly understood. The presynaptic role of multiple genes linked to PD including α-synuclein (α-syn) has suggested that LRRK2 may also influ...

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Detalles Bibliográficos
Autores principales: Maas, James W. Jr., Yang, Jing, Edwards, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322269/
https://www.ncbi.nlm.nih.gov/pubmed/28280464
http://dx.doi.org/10.3389/fnsyn.2017.00005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322269/
https://www.ncbi.nlm.nih.gov/pubmed/28280464
http://dx.doi.org/10.3389/fnsyn.2017.00005

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