Oxygen impairs oligodendroglial development via oxidative stress and reduced expression of HIF-1α

The premature increase of oxygen tension may contribute to oligodendroglial precursor cell (OPC) damage in preterm infants. Fetal OPCs are exposed to low oxygen tissue tensions not matched when cells are cultured in room air. Maturation (A2B5, O4, O1, MBP, CNP, arborization), oxidative stress (nitro...

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Detalles Bibliográficos
Autores principales: Brill, Christina, Scheuer, Till, Bührer, Christoph, Endesfelder, Stefanie, Schmitz, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322337/
https://www.ncbi.nlm.nih.gov/pubmed/28230075
http://dx.doi.org/10.1038/srep43000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322337/
https://www.ncbi.nlm.nih.gov/pubmed/28230075
http://dx.doi.org/10.1038/srep43000

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