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Macrophage Migration Inhibitory Factor is subjected to glucose modification and oxidation in Alzheimer’s Disease

Glucose and glucose metabolites are able to adversely modify proteins through a non-enzymatic reaction called glycation, which is associated with the pathology of Alzheimer’s Disease (AD) and is a characteristic of the hyperglycaemia induced by diabetes. However, the precise protein glycation profil...

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Detalles Bibliográficos
Autores principales: Kassaar, Omar, Pereira Morais, Marta, Xu, Suying, Adam, Emily L., Chamberlain, Rosemary C., Jenkins, Bryony, James, Tony, Francis, Paul T., Ward, Stephen, Williams, Robert J., van den Elsen, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322340/
https://www.ncbi.nlm.nih.gov/pubmed/28230058
http://dx.doi.org/10.1038/srep42874