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Macrophage Migration Inhibitory Factor is subjected to glucose modification and oxidation in Alzheimer’s Disease
Glucose and glucose metabolites are able to adversely modify proteins through a non-enzymatic reaction called glycation, which is associated with the pathology of Alzheimer’s Disease (AD) and is a characteristic of the hyperglycaemia induced by diabetes. However, the precise protein glycation profil...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322340/ https://www.ncbi.nlm.nih.gov/pubmed/28230058 http://dx.doi.org/10.1038/srep42874 |