Pentabromophenol suppresses TGF-β signaling by accelerating degradation of type II TGF-β receptors via caveolae-mediated endocytosis

Pentabromophenol (PBP), a brominated flame retardant (BFR), is widely used in various consumer products. BFRs exert adverse health effects such as neurotoxic and endocrine-disrupting effects. In this study, we found that PBP suppressed TGF-β response by accelerating the turnover rate of TGF-β recept...

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Detalles Bibliográficos
Autores principales: Chen, Chun-Lin, Yang, Pei-Hua, Kao, Yu-Chen, Chen, Pei-Yu, Chung, Chih-Ling, Wang, Shih-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322341/
https://www.ncbi.nlm.nih.gov/pubmed/28230093
http://dx.doi.org/10.1038/srep43206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322341/
https://www.ncbi.nlm.nih.gov/pubmed/28230093
http://dx.doi.org/10.1038/srep43206

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