Epitope Addition and Ablation via Manipulation of a Dengue Virus Serotype 1 Infectious Clone

Despite the clinical relevance, dengue virus (DENV) research has been hampered by the absence of robust reverse genetic systems to manipulate the viral serotypes for propagation and generation of mutant viruses. In this article, we describe application of an infectious clone system for DENV serotype...

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Detalles Bibliográficos
Autores principales: Gallichotte, Emily N., Menachery, Vineet D., Yount, Boyd L., Widman, Douglas G., Dinnon, Kenneth H., Hartman, Steven, de Silva, Aravinda M., Baric, Ralph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322348/
https://www.ncbi.nlm.nih.gov/pubmed/28251184
http://dx.doi.org/10.1128/mSphere.00380-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322348/
https://www.ncbi.nlm.nih.gov/pubmed/28251184
http://dx.doi.org/10.1128/mSphere.00380-16

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