Cargando…
Epitope Addition and Ablation via Manipulation of a Dengue Virus Serotype 1 Infectious Clone
Despite the clinical relevance, dengue virus (DENV) research has been hampered by the absence of robust reverse genetic systems to manipulate the viral serotypes for propagation and generation of mutant viruses. In this article, we describe application of an infectious clone system for DENV serotype...
Autores principales: | Gallichotte, Emily N., Menachery, Vineet D., Yount, Boyd L., Widman, Douglas G., Dinnon, Kenneth H., Hartman, Steven, de Silva, Aravinda M., Baric, Ralph S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322348/ https://www.ncbi.nlm.nih.gov/pubmed/28251184 http://dx.doi.org/10.1128/mSphere.00380-16 |
Ejemplares similares
-
Human dengue virus serotype 2 neutralizing antibodies target two distinct quaternary epitopes
por: Gallichotte, Emily N., et al.
Publicado: (2018) -
Transplantation of a quaternary structure neutralizing antibody epitope from dengue virus serotype 3 into serotype 4
por: Widman, Douglas G., et al.
Publicado: (2017) -
A New Quaternary Structure Epitope on Dengue Virus Serotype 2 Is the Target of Durable Type-Specific Neutralizing Antibodies
por: Gallichotte, E. N., et al.
Publicado: (2015) -
Genetic Variation between Dengue Virus Type 4 Strains Impacts Human Antibody Binding and Neutralization
por: Gallichotte, Emily N., et al.
Publicado: (2018) -
Shortening of Zika virus CD-loop reduces neurovirulence while preserving antigenicity
por: Dinnon III, Kenneth H., et al.
Publicado: (2019)