Optogenetic activation of VGLUT2-expressing excitatory neurons blocks epileptic seizure-like activity in the mouse entorhinal cortex

We investigated whether an anti-epileptic effect is obtained by selectively activating excitatory neurons expressing ChR2 under the promoter for the synaptic vesicular glutamate transporter 2 (VGLUT2). VGLUT2-expressing cells were optically stimulated while local field potential and whole-cell patch...

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Detalles Bibliográficos
Autores principales: Yekhlef, Latefa, Breschi, Gian Luca, Taverna, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322365/
https://www.ncbi.nlm.nih.gov/pubmed/28230208
http://dx.doi.org/10.1038/srep43230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322365/
https://www.ncbi.nlm.nih.gov/pubmed/28230208
http://dx.doi.org/10.1038/srep43230

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