Dezocine exhibits antihypersensitivity activities in neuropathy through spinal μ-opioid receptor activation and norepinephrine reuptake inhibition

Dezocine is the number one opioid painkiller prescribed and sold in China, occupying 44% of the nation’s opioid analgesics market today and far ahead of the gold-standard morphine. We discovered the mechanisms underlying dezocine antihypersensitivity activity and assessed their implications to antih...

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Detalles Bibliográficos
Autores principales: Wang, Yong-Xiang, Mao, Xiao-Fang, Li, Teng-Fei, Gong, Nian, Zhang, Ma-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322378/
https://www.ncbi.nlm.nih.gov/pubmed/28230181
http://dx.doi.org/10.1038/srep43137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322378/
https://www.ncbi.nlm.nih.gov/pubmed/28230181
http://dx.doi.org/10.1038/srep43137

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