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Dezocine exhibits antihypersensitivity activities in neuropathy through spinal μ-opioid receptor activation and norepinephrine reuptake inhibition
Dezocine is the number one opioid painkiller prescribed and sold in China, occupying 44% of the nation’s opioid analgesics market today and far ahead of the gold-standard morphine. We discovered the mechanisms underlying dezocine antihypersensitivity activity and assessed their implications to antih...
Autores principales: | Wang, Yong-Xiang, Mao, Xiao-Fang, Li, Teng-Fei, Gong, Nian, Zhang, Ma-Zhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322378/ https://www.ncbi.nlm.nih.gov/pubmed/28230181 http://dx.doi.org/10.1038/srep43137 |
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