Cargando…
α-synuclein transfer through tunneling nanotubes occurs in SH-SY5Y cells and primary brain pericytes from Parkinson’s disease patients
Parkinson’s disease (PD) is characterized by the presence of inclusions known as Lewy bodies, which mainly consist of α-synuclein (α-syn) aggregates. There is growing evidence that α-syn self-propagates in non-neuronal cells, thereby contributing to the progression and spread of PD pathology in the...
Autores principales: | Dieriks, Birger Victor, Park, Thomas I-H., Fourie, Chantelle, Faull, Richard L. M., Dragunow, Mike, Curtis, Maurice A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322400/ https://www.ncbi.nlm.nih.gov/pubmed/28230073 http://dx.doi.org/10.1038/srep42984 |
Ejemplares similares
-
Human pericytes degrade diverse α-synuclein aggregates
por: Dieriks, Birger Victor, et al.
Publicado: (2022) -
Pericytes take up and degrade α-synuclein but succumb to apoptosis under cellular stress
por: Stevenson, Taylor J., et al.
Publicado: (2022) -
Wrapping up the role of pericytes in Parkinson’s disease
por: Stevenson, Taylor John, et al.
Publicado: (2023) -
α-synuclein inclusions are abundant in non-neuronal cells in the anterior olfactory nucleus of the Parkinson’s disease olfactory bulb
por: Stevenson, Taylor J., et al.
Publicado: (2020) -
A ventral glomerular deficit in Parkinson’s disease revealed by whole olfactory bulb reconstruction
por: Zapiec, Bolek, et al.
Publicado: (2017)