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MicroRNA-Related Polymorphisms in PI3K/Akt/mTOR Pathway Genes Are Predictive of Limited-Disease Small Cell Lung Cancer Treatment Outcomes

The phosphoinositide-3 kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) signaling pathway plays an important role in cancer progression and treatment, including that of small cell lung cancer (SCLC), a disease with traditionally poor prognosis. Given the regulatory role of microRNA (miRNA) in...

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Detalles Bibliográficos
Autores principales: Jiang, Wei, Zhang, Wenjue, Wu, Lihong, Liu, Lipin, Men, Yu, Wang, Jingbo, Liang, Jun, Hui, Zhouguang, Zhou, Zongmei, Bi, Nan, Wang, Luhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322445/
https://www.ncbi.nlm.nih.gov/pubmed/28280736
http://dx.doi.org/10.1155/2017/6501385