Silencing CAPN2 Expression Inhibited Castration-Resistant Prostate Cancer Cells Proliferation and Invasion via AKT/mTOR Signal Pathway

The mRNA expression of CAPN2 was upregulated in CRPC cells (DU145 and PC3) than that in non-CRPC cells. Silencing CAPN2 expression could inhibit DU145 and PC3 cells proliferation by cell cycle arrest at G1 phase. Knockdown of CPAN2 level suppressed the migration and invasion capacity of CRPC cells b...

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Detalles Bibliográficos
Autores principales: Li, Pu, Miao, Chenkui, Liang, Chao, Shao, Pengfei, Wang, Zengjun, Li, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322456/
https://www.ncbi.nlm.nih.gov/pubmed/28280729
http://dx.doi.org/10.1155/2017/2593674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322456/
https://www.ncbi.nlm.nih.gov/pubmed/28280729
http://dx.doi.org/10.1155/2017/2593674

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