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Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate

Ageing associates with significant alterations in somatic/adult stem cells and therapies to counteract these might have profound benefits for health. In the blood, haematopoietic stem cell (HSC) ageing is linked to several functional shortcomings. However, besides the recent realization that individ...

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Detalles Bibliográficos
Autores principales: Wahlestedt, Martin, Erlandsson, Eva, Kristiansen, Trine, Lu, Rong, Brakebusch, Cord, Weissman, Irving L., Yuan, Joan, Martin-Gonzalez, Javier, Bryder, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322498/
https://www.ncbi.nlm.nih.gov/pubmed/28224997
http://dx.doi.org/10.1038/ncomms14533