MiRNA-21 mediates the antiangiogenic activity of metformin through targeting PTEN and SMAD7 expression and PI3K/AKT pathway

Metformin, an anti-diabetic drug commonly used for type 2 diabetes therapy, is associated with anti-angiogenic effects in conditions beyond diabetes. miR-21 has been reported to be involved in the process of angiogenesis. However, the precise regulatory mechanisms by which the metformin-induced endo...

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Detalles Bibliográficos
Autores principales: Luo, Mao, Tan, Xiaoyong, Mu, Lin, Luo, Yulin, Li, Rong, Deng, Xin, Chen, Ni, Ren, Meiping, Li, Yongjie, Wang, Liqun, Wu, Jianbo, Wan, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322530/
https://www.ncbi.nlm.nih.gov/pubmed/28230206
http://dx.doi.org/10.1038/srep43427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322530/
https://www.ncbi.nlm.nih.gov/pubmed/28230206
http://dx.doi.org/10.1038/srep43427

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