Fingolimod additionally acts as immunomodulator focused on the innate immune system beyond its prominent effects on lymphocyte recirculation

BACKGROUND: Growing evidence emphasizes the relevance of sphingolipids for metabolism and immunity of antigen-presenting cells (APC). APCs are key players in balancing tolerogenic and encephalitogenic responses in immunology. In contrast to the well-known prominent effects of sphingosine-1-phosphate...

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Detalles Bibliográficos
Autores principales: Thomas, Katja, Sehr, Tony, Proschmann, Undine, Rodriguez-Leal, Francisco Alejandro, Haase, Rocco, Ziemssen, Tjalf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322645/
https://www.ncbi.nlm.nih.gov/pubmed/28231856
http://dx.doi.org/10.1186/s12974-017-0817-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322645/
https://www.ncbi.nlm.nih.gov/pubmed/28231856
http://dx.doi.org/10.1186/s12974-017-0817-6

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