Efficacy of 1, 5, and 20 mg oral sildenafil in the treatment of adults with pulmonary arterial hypertension: a randomized, double-blind study with open-label extension

BACKGROUND: In a previous study, 6-minute walk distance (6MWD) improvement with sildenafil was not dose dependent at the 3 doses tested (20, 40, and 80 mg 3 times daily [TID]). This study assessed whether lower doses were less effective than the approved 20-mg TID dosage. METHODS: Treatment-naive pa...

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Detalles Bibliográficos
Autores principales: Vizza, Carmine Dario, Sastry, B. K. S., Safdar, Zeenat, Harnisch, Lutz, Gao, Xiang, Zhang, Min, Lamba, Manisha, Jing, Zhi-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322647/
https://www.ncbi.nlm.nih.gov/pubmed/28228114
http://dx.doi.org/10.1186/s12890-017-0374-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322647/
https://www.ncbi.nlm.nih.gov/pubmed/28228114
http://dx.doi.org/10.1186/s12890-017-0374-x

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