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Playing hide and seek with repeats in local and global de novo transcriptome assembly of short RNA-seq reads
BACKGROUND: The main challenge in de novo genome assembly of DNA-seq data is certainly to deal with repeats that are longer than the reads. In de novo transcriptome assembly of RNA-seq reads, on the other hand, this problem has been underestimated so far. Even though we have fewer and shorter repeat...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322684/ https://www.ncbi.nlm.nih.gov/pubmed/28250805 http://dx.doi.org/10.1186/s13015-017-0091-2 |