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Playing hide and seek with repeats in local and global de novo transcriptome assembly of short RNA-seq reads

BACKGROUND: The main challenge in de novo genome assembly of DNA-seq data is certainly to deal with repeats that are longer than the reads. In de novo transcriptome assembly of RNA-seq reads, on the other hand, this problem has been underestimated so far. Even though we have fewer and shorter repeat...

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Detalles Bibliográficos
Autores principales: Lima, Leandro, Sinaimeri, Blerina, Sacomoto, Gustavo, Lopez-Maestre, Helene, Marchet, Camille, Miele, Vincent, Sagot, Marie-France, Lacroix, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322684/
https://www.ncbi.nlm.nih.gov/pubmed/28250805
http://dx.doi.org/10.1186/s13015-017-0091-2