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A genetic interaction analysis identifies cancer drivers that modify EGFR dependency

A large number of cancer drivers have been identified through tumor sequencing efforts, but how they interact and the degree to which they can substitute for each other have not been systematically explored. To comprehensively investigate how cancer drivers genetically interact, we searched for modi...

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Detalles Bibliográficos
Autores principales: Liao, Sida, Davoli, Teresa, Leng, Yumei, Li, Mamie Z., Xu, Qikai, Elledge, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322732/
https://www.ncbi.nlm.nih.gov/pubmed/28167502
http://dx.doi.org/10.1101/gad.291948.116