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Targeting RNA for processing or destruction by the eukaryotic RNA exosome and its cofactors

The eukaryotic RNA exosome is an essential and conserved protein complex that can degrade or process RNA substrates in the 3′-to-5′ direction. Since its discovery nearly two decades ago, studies have focused on determining how the exosome, along with associated cofactors, achieves the demanding task...

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Detalles Bibliográficos
Autores principales: Zinder, John C., Lima, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322736/
https://www.ncbi.nlm.nih.gov/pubmed/28202538
http://dx.doi.org/10.1101/gad.294769.116