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Molecular and genetic alterations associated with therapy resistance and relapse of acute myeloid leukemia

BACKGROUND: The majority of individuals with acute myeloid leukemia (AML) respond to initial chemotherapy and achieve a complete remission, yet only a minority experience long-term survival because a large proportion of patients eventually relapse with therapy-resistant disease. Relapse therefore re...

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Detalles Bibliográficos
Autores principales: Hackl, Hubert, Astanina, Ksenia, Wieser, Rotraud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322789/
https://www.ncbi.nlm.nih.gov/pubmed/28219393
http://dx.doi.org/10.1186/s13045-017-0416-0