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Making the most of RNA-seq: Pre-processing sequencing data with Opossum for reliable SNP variant detection
RNA-seq (transcriptome sequencing) is primarily considered a method of gene expression analysis but it can also be used to detect DNA variants in expressed regions of the genome. However, current variant callers do not generally behave well with RNA-seq data due to reads encompassing intronic region...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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F1000Research
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322827/ https://www.ncbi.nlm.nih.gov/pubmed/28239666 http://dx.doi.org/10.12688/wellcomeopenres.10501.2 |