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A Simple and Sensitive High-Content Assay for the Characterization of Antiproliferative Therapeutic Antibodies
Monoclonal antibodies (mAbs) have become a central class of therapeutic agents in particular as antiproliferative compounds. Their often complex modes of action require sensitive assays during early, functional characterization. Current cell-based proliferation assays often detect metabolites that a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322830/ https://www.ncbi.nlm.nih.gov/pubmed/27909235 http://dx.doi.org/10.1177/1087057116677821 |