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Reversal of multidrug resistance in human lung cancer cells by delivery of 3-octadecylcarbamoylacrylic acid–cisplatin-based liposomes

Liposome-based drug delivery system would be an innovative and promising candidate to circumvent multidrug resistance (MDR) of cisplatin (CDDP). However, the reversal efficacy of liposomal CDDP was severely impaired by weak cellular uptake and insufficient intracellular drug release. In this study,...

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Detalles Bibliográficos
Autores principales: Song, Juan, Ren, Weifang, Xu, Tingting, Zhang, Yi, Guo, Hongyu, Zhu, Shanshan, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322835/
https://www.ncbi.nlm.nih.gov/pubmed/28255230
http://dx.doi.org/10.2147/DDDT.S124912