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ALKBH7 Variant Related to Prostate Cancer Exhibits Altered Substrate Binding

The search for prostate cancer biomarkers has received increased attention and several DNA repair related enzymes have been linked to this dysfunction. Here we report a targeted search for single nucleotide polymorphisms (SNPs) and functional impact characterization of human ALKBH family dioxygenase...

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Detalles Bibliográficos
Autores principales: Walker, Alice R., Silvestrov, Pavel, Müller, Tina A., Podolsky, Robert H., Dyson, Gregory, Hausinger, Robert P., Cisneros, Gerardo Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322872/
https://www.ncbi.nlm.nih.gov/pubmed/28231280
http://dx.doi.org/10.1371/journal.pcbi.1005345