Alterations in cellular pharmacokinetics and pharmacodynamics of elvitegravir in response to ethanol exposure in HIV-1 infected monocytic (U1) cells

Ethanol consumption is negatively associated with antiretroviral therapy (ART) adherence and general health in HIV positive individuals. Previously, we demonstrated ethanol-mediated alterations to metabolism of elvitegravir (EVG) in human liver microsomes. In the current study, we investigated ethan...

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Detalles Bibliográficos
Autores principales: Midde, Narasimha M., Sinha, Namita, Lukka, Pradeep B., Meibohm, Bernd, Kumar, Santosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322882/
https://www.ncbi.nlm.nih.gov/pubmed/28231276
http://dx.doi.org/10.1371/journal.pone.0172628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322882/
https://www.ncbi.nlm.nih.gov/pubmed/28231276
http://dx.doi.org/10.1371/journal.pone.0172628

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