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The intron in centromeric noncoding RNA facilitates RNAi-mediated formation of heterochromatin

In fission yeast, the formation of centromeric heterochromatin is induced through the RNA interference (RNAi)-mediated pathway. Some pre-mRNA splicing mutants (prp) exhibit defective formation of centromeric heterochromatin, suggesting that splicing factors play roles in the formation of heterochrom...

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Detalles Bibliográficos
Autores principales: Mutazono, Masatoshi, Morita, Misato, Tsukahara, Chihiro, Chinen, Madoka, Nishioka, Shiori, Yumikake, Tatsuhiro, Dohke, Kohei, Sakamoto, Misuzu, Ideue, Takashi, Nakayama, Jun-ichi, Ishii, Kojiro, Tani, Tokio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322907/
https://www.ncbi.nlm.nih.gov/pubmed/28231281
http://dx.doi.org/10.1371/journal.pgen.1006606