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The intron in centromeric noncoding RNA facilitates RNAi-mediated formation of heterochromatin
In fission yeast, the formation of centromeric heterochromatin is induced through the RNA interference (RNAi)-mediated pathway. Some pre-mRNA splicing mutants (prp) exhibit defective formation of centromeric heterochromatin, suggesting that splicing factors play roles in the formation of heterochrom...
Autores principales: | Mutazono, Masatoshi, Morita, Misato, Tsukahara, Chihiro, Chinen, Madoka, Nishioka, Shiori, Yumikake, Tatsuhiro, Dohke, Kohei, Sakamoto, Misuzu, Ideue, Takashi, Nakayama, Jun-ichi, Ishii, Kojiro, Tani, Tokio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322907/ https://www.ncbi.nlm.nih.gov/pubmed/28231281 http://dx.doi.org/10.1371/journal.pgen.1006606 |
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