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Osteosarcoma cell proliferation and survival requires mGluR5 receptor activity and is blocked by Riluzole

Osteosarcomas are malignant tumors of bone, most commonly seen in children and adolescents. Despite advances in modern medicine, the poor survival rate of metastatic osteosarcoma has not improved in two decades. In the present study we have investigated the effect of Riluzole on a human and mouse me...

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Detalles Bibliográficos
Autores principales: Liao, Sally, Ruiz, Yuleisy, Gulzar, Hira, Yelskaya, Zarina, Ait Taouit, Lyes, Houssou, Murielle, Jaikaran, Trisha, Schvarts, Yuriy, Kozlitina, Kristina, Basu-Roy, Upal, Mansukhani, Alka, Mahajan, Shahana S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322947/
https://www.ncbi.nlm.nih.gov/pubmed/28231291
http://dx.doi.org/10.1371/journal.pone.0171256