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Osteosarcoma cell proliferation and survival requires mGluR5 receptor activity and is blocked by Riluzole
Osteosarcomas are malignant tumors of bone, most commonly seen in children and adolescents. Despite advances in modern medicine, the poor survival rate of metastatic osteosarcoma has not improved in two decades. In the present study we have investigated the effect of Riluzole on a human and mouse me...
Autores principales: | Liao, Sally, Ruiz, Yuleisy, Gulzar, Hira, Yelskaya, Zarina, Ait Taouit, Lyes, Houssou, Murielle, Jaikaran, Trisha, Schvarts, Yuriy, Kozlitina, Kristina, Basu-Roy, Upal, Mansukhani, Alka, Mahajan, Shahana S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322947/ https://www.ncbi.nlm.nih.gov/pubmed/28231291 http://dx.doi.org/10.1371/journal.pone.0171256 |
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