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Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene
Cellular cholesterol metabolism is subject to tight regulation to maintain adequate levels of this central lipid molecule. Herein, the sterol-responsive Liver X Receptors (LXRs) play an important role owing to their ability to reduce cellular cholesterol load. In this context, identifying the full s...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322959/ https://www.ncbi.nlm.nih.gov/pubmed/28231341 http://dx.doi.org/10.1371/journal.pone.0172721 |