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Low-dose methotrexate enhances cycling of highly anaplastic cancer cells

We previously showed that cellular RedOx state governs the G(1)-S transition of AH130 hepatoma, a tumor spontaneously reprogrammed to the embryonic stem cell stage. This transition is impaired when the mithocondrial electron transport system is blocked by specific inhibitors (antimycin A) or the res...

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Detalles Bibliográficos
Autores principales: Cipolleschi, Maria Grazia, Marzi, Ilaria, Rovida, Elisabetta, Olivotto, Massimo, Dello Sbarba, Persio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323031/
https://www.ncbi.nlm.nih.gov/pubmed/27841718
http://dx.doi.org/10.1080/15384101.2016.1252883