Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells

Exposure of breast cancer cells to hypoxia increases the percentage of breast cancer stem cells (BCSCs), which are required for tumor initiation and metastasis, and this response is dependent on the activity of hypoxia-inducible factors (HIFs). We previously reported that exposure of breast cancer c...

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Detalles Bibliográficos
Autores principales: Zhang, Chuanzhao, Zhi, Wanqing Iris, Lu, Haiquan, Samanta, Debangshu, Chen, Ivan, Gabrielson, Edward, Semenza, Gregg L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323097/
https://www.ncbi.nlm.nih.gov/pubmed/27590511
http://dx.doi.org/10.18632/oncotarget.11743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323097/
https://www.ncbi.nlm.nih.gov/pubmed/27590511
http://dx.doi.org/10.18632/oncotarget.11743

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