Cargando…

Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells

Exposure of breast cancer cells to hypoxia increases the percentage of breast cancer stem cells (BCSCs), which are required for tumor initiation and metastasis, and this response is dependent on the activity of hypoxia-inducible factors (HIFs). We previously reported that exposure of breast cancer c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Chuanzhao, Zhi, Wanqing Iris, Lu, Haiquan, Samanta, Debangshu, Chen, Ivan, Gabrielson, Edward, Semenza, Gregg L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Priority Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323097/ https://www.ncbi.nlm.nih.gov/pubmed/27590511 http://dx.doi.org/10.18632/oncotarget.11743

Ejemplares similares

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype
por: Xiang, Lisha, et al.
Publicado: (2014)

Maintenance of redox homeostasis by hypoxia-inducible factors
por: Samanta, Debangshu, et al.
Publicado: (2017)

PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia
por: Luo, Weibo, et al.
Publicado: (2016)

Hypoxia-inducible factors enhance glutamate signaling in cancer cells
por: Hu, Hongxia, et al.
Publicado: (2014)

Anthracyclines suppress pheochromocytoma cell characteristics, including metastasis, through inhibition of the hypoxia signaling pathway
por: Pang, Ying, et al.
Publicado: (2017)

ZNF131 suppresses centrosome fragmentation in glioblastoma stem-like cells through regulation of HAUS5
por: Ding, Yu, et al.
Publicado: (2017)

HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells
por: Xiang, Lisha, et al.
Publicado: (2015)

Hypoxia-inducible factors: cancer progression and clinical translation
por: Wicks, Elizabeth E., et al.
Publicado: (2022)

Heat acclimation and cross tolerance to hypoxia: Bridging the gap between cellular and systemic responses
por: Ely, Brett R, et al.
Publicado: (2014)

Hypoxia and Hypoxia-Inducible Factors in Lymphedema
por: Jiang, Xinguo, et al.
Publicado: (2022)

MiR-203 Suppresses ZNF217 Upregulation in Colorectal Cancer and Its Oncogenicity
por: Li, Zewu, et al.
Publicado: (2015)

The dark side of ZNF217, a key regulator of tumorigenesis with powerful biomarker value
por: Cohen, Pascale A., et al.
Publicado: (2015)

Exploring the Significance of the Exon 4-Skipping Isoform of the ZNF217 Oncogene in Breast Cancer
por: Bellanger, Aurélie, et al.
Publicado: (2021)

The Intricate Interplay between the ZNF217 Oncogene and Epigenetic Processes Shapes Tumor Progression
por: Fahmé, Pia, et al.
Publicado: (2022)

Comparison of SARS-CoV-2 RT-PCR on a high-throughput molecular diagnostic platform and the cobas SARS-CoV-2 test for the diagnostic of COVID-19 on various clinical samples
por: Opota, Onya, et al.
Publicado: (2020)

Retraction: MiR-203 Suppresses ZNF217 Upregulation in Colorectal Cancer and Its Oncogenicity
Publicado: (2020)

Prolonged self-paced exercise in the heat – environmental factors affecting performance
por: Junge, Nicklas, et al.
Publicado: (2016)

AMP-activated kinase (AMPK) regulates activity of HER2 and EGFR in breast cancer
por: Jhaveri, Teraneh Z., et al.
Publicado: (2015)

Pyruvate kinase M2 regulates glucose metabolism by functioning as a coactivator for hypoxia-inducible factor 1 in cancer cells
por: Luo, Weibo, et al.
Publicado: (2011)

Global analysis of ZNF217 chromatin occupancy in the breast cancer cell genome reveals an association with ERalpha
por: Frietze, Seth, et al.
Publicado: (2014)

Elevated expression of ZNF217 promotes prostate cancer growth by restraining ferroportin-conducted iron egress
por: Jiang, Xingkang, et al.
Publicado: (2016)

Zinc finger gene 217 (ZNF217) Promoted Ovarian Hyperstimulation Syndrome (OHSS) through Regulating E(2) Synthesis and Inhibiting Thrombospondin-1 (TSP-1)
por: Zhai, Junyu, et al.
Publicado: (2017)

Targeting hypoxic microenvironment of pancreatic xenografts with the hypoxia-activated prodrug TH-302
por: Lohse, Ines, et al.
Publicado: (2016)

Chronic Activation of Corticotropin-Releasing Factor Type 2 Receptors Reveals a Key Role for 5-HT1A Receptor Responsiveness in Mediating Behavioral and Serotonergic Responses to Stressful Challenge
por: Neufeld-Cohen, Adi, et al.
Publicado: (2012)

HIF-1 Interacts with TRIM28 and DNA-PK to release paused RNA polymerase II and activate target gene transcription in response to hypoxia
por: Yang, Yongkang, et al.
Publicado: (2022)

Activation of hypoxia signaling induces phenotypic transformation of glioma cells: implications for bevacizumab antiangiogenic therapy
por: Xu, Hui, et al.
Publicado: (2015)

ZNF217 confers resistance to the pro-apoptotic signals of paclitaxel and aberrant expression of Aurora-A in breast cancer cells
por: Thollet, Aurélie, et al.
Publicado: (2010)

Oncogenic protein SALL4 and ZNF217 as prognostic indicators in solid cancers: a meta-analysis of individual studies
por: Cheng, Ji, et al.
Publicado: (2016)

Evaluating ZNF217 mRNA Expression Levels as a Predictor of Response to Endocrine Therapy in ER+ Breast Cancer
por: Vendrell, Julie A., et al.
Publicado: (2019)

OIP5-AS1/miR-137/ZNF217 Axis Promotes Malignant Behaviors in Epithelial Ovarian Cancer
por: Guo, Linlin, et al.
Publicado: (2020)

Retracted Article: Berberine alleviates amyloid beta-induced injury in Alzheimer's disease by miR-107/ZNF217
por: Wang, Jing, et al.
Publicado: (2019)

Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways
por: Valli, Alessandro, et al.
Publicado: (2014)

The ZNF217 Biomarker Predicts Low- and High-Risk Oncotype DX(®) Recurrence Score in ER-Positive Invasive Breast Cancers
por: Cohen, Pascale A., et al.
Publicado: (2019)

Prognostic relevance of miRNA-155 methylation in anaplastic glioma
por: Schliesser, Maximilian Georg, et al.
Publicado: (2016)

Macrophage Migration Inhibitory Factor Activates Hypoxia-Inducible Factor in a p53-Dependent Manner
por: Oda, Seiko, et al.
Publicado: (2008)

Syringaresinol protects against hypoxia/reoxygenation-induced cardiomyocytes injury and death by destabilization of HIF-1α in a FOXO3-dependent mechanism
por: Cho, Siyoung, et al.
Publicado: (2014)

CFC1 is a cancer stemness-regulating factor in neuroblastoma
por: Chikaraishi, Koji, et al.
Publicado: (2017)

Oxygen-regulated transcription factors and their role in pulmonary disease
por: Semenza, Gregg L
Publicado: (2000)

Multimodal targeting of tumor vasculature and cancer stem-like cells in sarcomas with VEGF-A inhibition, HIF-1α inhibition, and hypoxia-activated chemotherapy
por: Yoon, Changhwan, et al.
Publicado: (2016)

Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition
por: Ledaki, Ioanna, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_gmoe552eb33rf1tlkmsg3d7rt2