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p27(kip1) expression limits H-Ras-driven transformation and tumorigenesis by both canonical and non-canonical mechanisms

The tumor suppressor protein p27(Kip1) plays a pivotal role in the control of cell growth and metastasis formation. Several studies pointed to different roles for p27(Kip1) in the control of Ras induced transformation, although no explanation has been provided to elucidate these differences. We rece...

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Detalles Bibliográficos
Autores principales: Pellizzari, Ilenia, Fabris, Linda, Berton, Stefania, Segatto, Ilenia, Citron, Francesca, D'Andrea, Sara, Cusan, Martina, Benevol, Sara, Perin, Tiziana, Massarut, Samuele, Canzonieri, Vincenzo, Schiappacassi, Monica, Belletti, Barbara, Baldassarre, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323099/
https://www.ncbi.nlm.nih.gov/pubmed/27579539
http://dx.doi.org/10.18632/oncotarget.11656