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Renal tubular epithelium-targeted peroxisome proliferator-activated receptor-γ maintains the epithelial phenotype and antagonizes renal fibrogenesis

Accumulating evidence suggests that loss of the renal tubular epithelial phenotype plays an important role in the pathogenesis of renal tubulointerstitial fibrosis. Systemic activation of peroxisome proliferator-activated receptor γ (PPAR-γ) has been shown to be protective against renal fibrosis, al...

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Detalles Bibliográficos
Autores principales: Zhao, Min, Chen, Ying, Ding, Guixia, Xu, Ying, Bai, Mi, Zhang, Yue, Jia, Zhanjun, Huang, Songming, Zhang, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323108/
https://www.ncbi.nlm.nih.gov/pubmed/27602490
http://dx.doi.org/10.18632/oncotarget.11811