Expression of non-secreted IL-4 is associated with HDAC inhibitor-induced cell death, histone acetylation and c-Jun regulation in human gamma/delta T-cells

Previously, the expression of a non-secreted IL-4 variant (IL-4δ(13)) has been described in association with apoptosis and age-dependent Th2 T-cell polarization. Signaling pathways involved in this process have so far not been studied. Here we report the induction of IL-4δ(13) expression in human γδ...

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Detalles Bibliográficos
Autores principales: Bhat, Jaydeep, Sosna, Justyna, Fritsch, Jürgen, Quabius, Elgar Susanne, Schütze, Stefan, Zeissig, Sebastian, Ammerpohl, Ole, Adam, Dieter, Kabelitz, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323112/
https://www.ncbi.nlm.nih.gov/pubmed/27556516
http://dx.doi.org/10.18632/oncotarget.11462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323112/
https://www.ncbi.nlm.nih.gov/pubmed/27556516
http://dx.doi.org/10.18632/oncotarget.11462

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