Bone marrow adipocytes promote the Warburg phenotype in metastatic prostate tumors via HIF-1α activation

Metabolic adaptation is increasingly recognized as a key factor in tumor progression, yet its involvement in metastatic bone disease is not understood. Bone is as an adipocyte-rich organ, and a major site of metastasis from prostate cancer. Bone marrow adipocytes are metabolically active cells capab...

Descripción completa

Detalles Bibliográficos
Autores principales: Diedrich, Jonathan D., Rajagurubandara, Erandi, Herroon, Mackenzie K., Mahapatra, Gargi, Hüttemann, Maik, Podgorski, Izabela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323121/
https://www.ncbi.nlm.nih.gov/pubmed/27588494
http://dx.doi.org/10.18632/oncotarget.11712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323121/
https://www.ncbi.nlm.nih.gov/pubmed/27588494
http://dx.doi.org/10.18632/oncotarget.11712

Ejemplares similares